Análise de transmissão e da dinâmica de modificação de genótipos de Mycobacterium turbeculosis na Região Metropolitana de Vitória-ES em um intervalo de 10 anos

Abstract

Introduction: Molecular epidemiology have contributed to the understanding of the dynamic of transmission of tuberculosis (TB). Although many papers have been published on this subject, few studies, however, were performed taking into account the dynamic of modification of genotypic profiles of M. tuberculosis (Mtb) in a long time frame. Objective: To identify genotypes and factors associated with cluster size of Mtb in the population of the Metropolitan Area of Vitória – ES (RMV) and to analyze the dynamic of modification of Mtb genotypes in the RMV in a 10 years frame. Methods: This study had two parts.